Preheat your oven to 350°F (175°C) and line a large baking sheet with parchment paper.
In a large bowl, mix the Chex cereal, pretzels, and nuts.
In a saucepan over low heat, melt the butter, then stir in the hot honey until combined.
Remove from heat and mix in garlic powder, smoked paprika, and chili flakes if desired.
Pour the honey mixture over the dry ingredients and toss until evenly coated.
Spread the mixture on the prepared baking sheet and bake for about 20 minutes, stirring halfway through.
Let cool completely before serving.